O’Reilly EM, Torreggiani W (2019) Incidence of asymptomatic Chiari malformation. Meadows J et al (2000) Asymptomatic Chiari Type I malformations identified on magnetic resonance imaging. Whitson WJ et al (2015) A prospective natural history study of nonoperatively managed Chiari I malformation: does follow-up MRI surveillance alter surgical decision making? J Neurosurg Pediatr 16(2):159–166 Ann Otol Rhinol Laryngol 117(6):443–447ĭavidson L et al (2021) Long-term outcomes for children with an incidentally discovered Chiari malformation type 1: what is the clinical significance? Childs Nerv Syst 37(4):1191–1197 Simons JP, Ruscetta MN, Chi DH (2008) Sensorineural hearing impairment in children with Chiari I malformation. Pediatr Neurosurg 51(5):236–243Ībel F, Tahir MZ (2019) Role of sleep study in children with Chiari malformation and sleep disordered breathing. Lacy M et al (2016) Parent-reported executive dysfunction in children and adolescents with Chiari Malformation Type 1. Shaikh AG, Ghasia FF (2015) Neuro-ophthalmology of type 1 Chiari malformation. Tubbs RS et al (2011) Institutional experience with 500 cases of surgically treated pediatric Chiari malformation Type I. Sari SA, Ozum U (2021) The executive functions, intellectual capacity, and psychiatric disorders in adolescents with Chiari malformation type 1. Kumar A, Patni AH, Charbel F (2002) The Chiari I malformation and the neurotologist. Still, given their cranial and brain morphology, these cases may be at risk for adult-onset symptomatic CMI.Ĭhiari C (2021) Available from: Īmin R et al (2015) The association between sleep-disordered breathing and magnetic resonance imaging findings in a pediatric cohort with Chiari 1 malformation. ![]() ICTE alone did not appear to cause any unrecognized CMI symptoms and had no impact on the subjects’ current mental, physical, or behavioral health. ![]() This study demonstrated that pediatric ICTE subjects have similar PCF morphometrics to adult CMI. No significant differences were found among the 22 health instruments between the two groups. ![]() For males, the clivus bone length was significantly shorter ( p = 0.0002) for the ICTE group compared to controls. Notably, for females, the anterior CSF space was significantly smaller ( p = 0.00005) for the ICTE group than controls. Twelve and 15 measures were significantly different between the ICTE and control groups for females and males, respectively. Twenty-two brain morphometrics and 22 health instruments were compared between the two groups to identify unrecognized CMI symptoms and assess the general health impact of ICTE. ![]() Subjects were matched by sex, age, body mass index, race, and ethnicity. One-hundred-six subjects with ICTE and 106 matched controls without ICTE were identified from 11,411 anatomical MRI of healthy screened pediatric subjects from the ABCD project. The present study examined posterior cranial fossa (PCF) morphometrics and a broad range of health instruments of pediatric ICTE cases and matched controls extracted from the Adolescent Brain Cognitive Development (ABCD) dataset. Incidental cerebellar tonsillar ectopia (ICTE) that meets the radiographic criterion for Chiari malformation type I (CMI) is an increasingly common finding in the clinical setting, but its significance is unclear.
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